Gender specific influence of serotonin on core symptoms and neurodevelopment of autism spectrum disorders: A multicenter study in China

Table 1 Demographic characteristics of the participants in TD and ASD groups

Variable	TD (n = 1270)	ASD (n = 1387)	Z/chi-square	P
Age (years), Median (IQR)	4.42 (3.38–5.38)	3.96 (3.13–4.90)	− 6.290	<0.001
Gender, n(%)
Boys	832 (65.51)	1137 (81.98)	93.640	<0.001
Girls	438 (34.49)	250 (18.02)	93.640	<0.001
Boys	n = 806	n = 952
Z_HA, Median (IQR)	0.01 (− 0.64, 0.81)	0.24 (− 0.52, 0.93)	− 2.248	0.025
Z_WA, Median (IQR)	0.27 (− 0.38, 0.88)	0.36 (− 0.35, 1.05)	− 1.251	0.211
Z_BMIA, Median (IQR)	0.30 (− 0.41, 1.09)	0.26 (− 0.44, 1.09)	− 0.568	0.570
Girls	n = 420	n = 204
Z_HA, Median (IQR)	0.06 (− 0.66, 0.65)	0.26 (− 0.52, 0.98)	− 2.437	0.015
Z_WA, Median (IQR)	0.17 (− 0.48, 0.73)	0.22 (− 0.45, 0.85)	− 0.883	0.377
Z_BMIA, Median (IQR)	0.15 (− 0.50, 0.82)	0.03 (− 0.61, 0.76)	− 1.049	0.294

Data was shown as Median (IQR) or number (percentage). Chi-square test and Mann-Whitney U test were used in the analysis
ASD autism spectrum disorder, TD typically developing, IQR interquartile range, Z_HA Z-score of Height-for-Age, Z_WA Z-score of Weight-for-Age, Z_BMIA Z-score of BMI-for-Age

ISSN: 1753-2000