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Table 7 The serum 5-HT levels among ASD boys with different neurodevelopmental levels

From: Gender specific influence of serotonin on core symptoms and neurodevelopment of autism spectrum disorders: A multicenter study in China

Scale scores

5-HT Median (IQR)

Wald chi-square

P-value

ASD without DD (n = 259)

133.00 (95.00–181.00)

6.304

0.043

ASD with mild DD (n = 264)

137.00 (98.00–180.00)

ASD with moderate-severe DD (n = 288)

149.00 (103.25–198.75)*

  1. Generalized linear models (GLM) with gamma regression were employed to compare the serum 5-HT levels between the three groups, with age as covariate. “*” represents a significant difference between the ASD group without DD and the ASD group with moderate-severe DD, P = 0.015
  2. DD development disorder, ASD autism spectrum disorder, IQR interquartile range
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Child and Adolescent Psychiatry and Mental Health

ISSN: 1753-2000